Health Care [ 4/12 ] | Biotechnology [ 13/75 ]
NASDAQ | Common Stock
Olema Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapies for women's cancers.
The company's lead product candidate is palazestrant, an estrogen receptor (ER) antagonist and a selective ER degrader, which is in Phase 3 clinical trial for the treatment of recurrent, locally advanced, or metastatic ER-positive, human epidermal growth factor receptor 2-negative breast cancer; OPERA-01, the pivotal Phase 3 clinical trial of palazestrant as a monotherapy in second/third-line ER+/HER2- metastatic breast cancer; and palazestrant with CDK4/6 inhibitors, a phosphatidylinositol 3 kinase alpha (PI3Ka) inhibitor alpelisib, a mechanistic target of rapamycin inhibitor, and a CDK4 inhibitor that is in Phase 1b/2 clinical trial for the treatment of ER+/HER2- advanced or metastatic breast cancer.
It also develops OP-3136, an orally-available small molecule that potently and selectively inhibits KAT6 which is in Phase 1 clinical trials for patients with breast and other solid tumor cancers.
The company was formerly known as CombiThera, Inc. and changed its name to Olema Pharmaceuticals, Inc. in March 2009.
Olema Pharmaceuticals, Inc. was incorporated in 2006 and is headquartered in San Francisco, California.
| Reported date | EPSChange YoY | EstimateSurprise |
|---|---|---|
| Mar 2, 26 | -0.50 Increased by +1.10% | -0.52 Increased by +3.28% |
| Nov 10, 25 | -0.49 Increased by +18.33% | -0.47 Decreased by -4.21% |
| Aug 11, 25 | -0.51 Increased by +5.56% | -0.38 Decreased by -34.21% |
| May 6, 25 | -0.36 Increased by +35.71% | -0.55 Increased by +34.55% |
| Mar 10, 25 | -0.51 Decreased by -4.08% | 0.17 Decreased by -394.46% |
| Nov 5, 24 | -0.60 Decreased by -25.00% | -0.58 Decreased by -3.45% |
| Aug 6, 24 | -0.54 Decreased by -10.20% | -0.55 Increased by +1.82% |
| May 8, 24 | -0.56 Increased by +20.00% | -0.55 Decreased by -1.82% |
| Fiscal ending date | RevenueChange YoY | IncomeChange YoY | ProfitChange YoY |
|---|---|---|---|
| Dec 31, 25 | 0.00 Decreased by -100.00% | -46.06 M Decreased by -37.22% | Decreased by N/A% Decreased by N/A% |
| Sep 30, 25 | 0.00 Decreased by N/A% | -42.22 M Decreased by -22.17% | Decreased by N/A% Decreased by N/A% |
| Jun 30, 25 | 0.00 Decreased by N/A% | -43.78 M Decreased by -44.11% | Decreased by N/A% Decreased by N/A% |
| Mar 31, 25 | 0.00 Decreased by N/A% | -30.39 M Increased by +1.88% | Decreased by N/A% Decreased by N/A% |
| Dec 31, 24 | 364.00 K Decreased by -80.68% | -33.57 M Decreased by -25.38% | Decreased by -9.22 K% Decreased by -548.95% |
| Sep 30, 24 | 0.00 Decreased by N/A% | -34.55 M Decreased by -60.71% | Decreased by N/A% Decreased by N/A% |
| Jun 30, 24 | 0.00 Decreased by N/A% | -30.38 M Decreased by -51.19% | Decreased by N/A% Decreased by N/A% |
| Mar 31, 24 | 0.00 Decreased by N/A% | -30.97 M Decreased by -9.49% | Decreased by N/A% Decreased by N/A% |