| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bain Capital Life Sciences Investors, LLC | 8.51M (12.62%) | 1.66M Increased by +19.56% | Dec 31, 25 |
| 2 | Paradigm Biocapital Advisors LP | 7.54M (11.19%) | 750.00K Increased by +9.94% | Dec 31, 25 |
| 3 | Bvf Inc | 5.30M (7.85%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 4 | FMR Inc | 5.02M (7.45%) | 4.99M Increased by +99.41% | Dec 31, 25 |
| 5 | BlackRock Inc | 4.73M (7.01%) | 121.28K Increased by +2.57% | Sep 30, 25 |
| 6 | HHG PLC | 3.59M (5.32%) | 563.07K Increased by +15.70% | Sep 30, 25 |
| 7 | Vanguard Group Inc | 3.56M (5.28%) | 364.04K Increased by +10.22% | Dec 31, 25 |
| 8 | Deep Track Capital, LP | 3.47M (5.15%) | 27.34K Increased by +0.79% | Sep 30, 25 |
| 9 | Siren, L.L.C. | 3.30M (4.90%) | 3.30M Increased by +100.00% | Dec 31, 25 |
| 10 | Logos Global Management LP | 3.21M (4.76%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 11 | State Street Corporation | 3.18M (4.71%) | 2.51M Increased by +78.82% | Mar 31, 24 |
| 12 | Franklin Resources Inc | 3.01M (4.47%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 13 | Cormorant Asset Management, LLC | 2.75M (4.08%) | 2.75M Increased by +100.00% | Dec 31, 25 |
| 14 | RA Capital Management, LLC | 2.60M (3.86%) | 2.60M Increased by +100.00% | Dec 31, 25 |
| 15 | MPM Oncology Impact Management LP | 2.38M (3.53%) | -551.68K Decreased by -23.19% | Jun 30, 25 |
| 16 | Lightspeed Management Co LLC | 1.93M (2.86%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 17 | Pictet Asset Manangement SA | 1.88M (2.79%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | State Street Corp | 1.86M (2.75%) | -112.44K Decreased by -6.05% | Dec 31, 24 |
| 19 | venBio Select Advisor LLC | 1.65M (2.45%) | 1.65M Increased by +100.00% | Dec 31, 24 |
| 20 | Vestal Point Capital LP | 1.65M (2.45%) | 1.65M Increased by +100.00% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.24M (3.33%) | 4.95K Increased by +0.22% | Feb 28, 26 |
| 2 | Polar Capital Healthcare Opports Inc | 1.60M (2.38%) | 1.60M Increased by +100.00% | Jan 31, 26 |
| 3 | Vanguard US Total Market Shares ETF | 1.49M (2.21%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 1.45M (2.15%) | 1.45M Increased by +100.00% | Feb 28, 26 |
| 5 | Fidelity Select Health Care | 1.28M (1.90%) | 330.00K Increased by +25.78% | Jan 31, 26 |
| 6 | Franklin Biotechnology Discv A(acc)USD | 1.22M (1.81%) | -100.64K Decreased by -8.24% | Dec 31, 25 |
| 7 | Belfius Equities Cure C Cap | 1.04M (1.54%) | 0.00 Increased by 0.00% | Nov 30, 25 |
| 8 | Pictet-Biotech P USD | 931.49K (1.38%) | 11.40K Increased by +1.22% | May 31, 25 |
| 9 | Franklin Small Cap Growth SMA | 917.80K (1.36%) | 917.80K Increased by +100.00% | Jun 30, 25 |
| 10 | Franklin Small Cap Growth Adv | 893.20K (1.32%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 11 | SPDR® S&P Biotech ETF | 864.83K (1.28%) | -5.26K Decreased by -0.61% | Feb 28, 25 |
| 12 | Candriam Global Equities Oncology | 860.55K (1.28%) | 187.55K Increased by +21.79% | Sep 30, 24 |
| 13 | Pictet-Global Megatrend Sel I USD | 795.67K (1.18%) | 12.16K Increased by +1.53% | May 31, 25 |
| 14 | Fidelity Advisor Biotechnology I | 782.80K (1.16%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 15 | Columbia Small Cap Value Discv A | 778.62K (1.15%) | 21.40K Increased by +2.75% | Jul 31, 25 |
| 16 | Columbia Small Cap Value I A | 778.62K (1.15%) | 21.40K Increased by +2.75% | Jul 31, 25 |
| 17 | Columbia Small Cap Value Discovery Fund | 757.22K (1.12%) | 241.23K Increased by +31.86% | Jun 30, 25 |
| 18 | Columbia Small Cap Value I | 757.22K (1.12%) | 241.23K Increased by +31.86% | Jun 30, 25 |
| 19 | State Street® SPDR® S&P® Biotech ETF | 749.12K (1.11%) | 4.16K Increased by +0.56% | Feb 28, 26 |
| 20 | Strategic Advisers Fidelity US TtlStk | 730.80K (1.08%) | 607.40K Increased by +83.11% | Jan 31, 26 |