| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LLC | 6.96M (0.68%) | 4.67M Increased by +67.07% | Dec 31, 25 |
| 2 | Capital World Investors | 6.08M (0.60%) | 41.48K Increased by +0.68% | Sep 30, 25 |
| 3 | Principal Financial Group Inc | 2.88M (0.28%) | 1.12M Increased by +38.89% | Mar 31, 25 |
| 4 | Mirae Asset Global Investments (Korea) Co Ltd | 2.13M (0.21%) | 2.13M Increased by +99.78% | Mar 31, 25 |
| 5 | HHG PLC | 2.05M (0.20%) | -148.32K Decreased by -7.24% | Sep 30, 25 |
| 6 | Viking Global Investors LP | 1.95M (0.19%) | -87.44K Decreased by -4.48% | Sep 30, 24 |
| 7 | Frazier Life Sciences Management, L.P. | 1.90M (0.19%) | 275.00K Increased by +14.46% | Dec 31, 25 |
| 8 | Amvescap Plc. | 1.89M (0.19%) | -1.32M Decreased by -69.49% | Dec 31, 23 |
| 9 | ClearBridge Advisors, LLC | 1.81M (0.18%) | -1.71M Decreased by -94.65% | Dec 31, 25 |
| 10 | Citadel Advisors Llc | 1.69M (0.17%) | 700.80K Increased by +41.52% | Dec 31, 25 |
| 11 | Segantii Capital Management Ltd | 1.56M (0.15%) | -131.64K Decreased by -8.46% | Mar 31, 24 |
| 12 | FMR Inc | 1.44M (0.14%) | -3.26M Decreased by -226.42% | Dec 31, 25 |
| 13 | BAMCO Inc | 1.42M (0.14%) | 46.76K Increased by +3.30% | Dec 31, 25 |
| 14 | RA Capital Management, LLC | 1.30M (0.13%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 15 | ADAR1 Capital Management LLC | 1.25M (0.12%) | 377.74K Increased by +30.30% | Dec 31, 25 |
| 16 | Woodline Partners LP | 1.20M (0.12%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 17 | Paradigm Biocapital Advisors LP | 1.09M (0.11%) | -50.60K Decreased by -4.64% | Dec 31, 23 |
| 18 | Genesis Investment Management, LLP | 1.03M (0.10%) | -320.06K Decreased by -31.01% | Sep 30, 23 |
| 19 | T. Rowe Price Associates, Inc. | 948.67K (0.09%) | 795.63K Increased by +83.87% | Sep 30, 25 |
| 20 | Allianz Asset Management AG | 815.00K (0.08%) | -117.00K Decreased by -14.36% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds New World A | 3.27M (0.32%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Capital Group New Geography Equity Comp | 3.27M (0.32%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | American Funds SMALLCAP World A | 2.08M (0.20%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | ClearBridge International Growth C | 2.02M (0.20%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 5 | ClearBridge International Growth EAFE | 2.02M (0.20%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 6 | Invesco Developing Markets A | 1.67M (0.16%) | -281.32K Decreased by -16.89% | Dec 31, 23 |
| 7 | Invesco Emerging Markets Equity | 1.67M (0.16%) | -1.16M Decreased by -69.61% | Dec 31, 23 |
| 8 | Fidelity Contrafund | 1.66M (0.16%) | 260.35K Increased by +15.70% | Jul 31, 25 |
| 9 | Principal International Eq Fd - Gross | 1.32M (0.13%) | 0.00 Increased by 0.00% | May 31, 25 |
| 10 | Baron Emerging Markets Institutional | 1.18M (0.12%) | 32.77K Increased by +2.78% | Dec 31, 25 |
| 11 | Baron Emerging Markets Strategy | 1.18M (0.12%) | 32.77K Increased by +2.78% | Dec 31, 25 |
| 12 | Janus Selection Global Life Science AUSD | 1.16M (0.11%) | -10.32K Decreased by -0.89% | Jun 30, 24 |
| 13 | Vanguard Health Care Inv | 1.10M (0.11%) | -1.79M Decreased by -162.65% | Mar 31, 25 |
| 14 | Janus Henderson Intl Alpha Equity | 772.96K (0.08%) | -1.99M Decreased by -257.87% | Mar 31, 25 |
| 15 | T. Rowe Price New Horizons | 750.19K (0.07%) | -172.30K Decreased by -22.97% | Dec 31, 23 |
| 16 | US Small-Cap Growth II Equity Comp | 750.19K (0.07%) | -172.60K Decreased by -23.01% | Dec 31, 23 |
| 17 | Allianz Oriental Income P USD | 709.33K (0.07%) | -1.14K Decreased by -0.16% | Jul 31, 25 |
| 18 | Principal Div Intl Eq Fd T-III | 646.98K (0.06%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 19 | Principal International All Country Eq | 646.98K (0.06%) | 646.98K Increased by +100.00% | Dec 31, 24 |
| 20 | Janus Henderson VIT Overseas Instl | 630.73K (0.06%) | 127.31K Increased by +20.18% | Sep 30, 24 |