| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 8.68M (18.13%) | 124.30K Increased by +1.43% | Sep 30, 23 |
| 2 | Deerfield Management Co | 6.72M (14.03%) | 885.93K Increased by +13.19% | Sep 30, 24 |
| 3 | Affinity Asset Advisors, LLC | 6.48M (13.55%) | 2.56M Increased by +39.48% | Dec 31, 25 |
| 4 | Capital Research & Mgmt Co - Division 3 | 5.25M (10.97%) | 2.89M Increased by +55.14% | Jun 30, 24 |
| 5 | Vanguard Group Inc | 3.94M (8.24%) | 173.57K Increased by +4.40% | Dec 31, 25 |
| 6 | T. Rowe Price Associates, Inc. | 3.83M (8.00%) | -122.74K Decreased by -3.21% | Sep 30, 23 |
| 7 | UBS Group AG | 3.78M (7.90%) | 2.59M Increased by +68.34% | Dec 31, 24 |
| 8 | Farallon Capital Management, L.L.C. | 3.17M (6.62%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 9 | TANG CAPITAL MANAGEMENT LLC | 2.81M (5.88%) | -286.00K Decreased by -10.16% | Dec 31, 25 |
| 10 | Octagon Capital Advisors LP | 2.39M (5.00%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 11 | Baker Bros Advisors LP | 2.35M (4.91%) | 1.33M Increased by +56.45% | Dec 31, 25 |
| 12 | Marshall Wace Asset Management Ltd | 2.32M (4.84%) | -80.55K Decreased by -3.48% | Sep 30, 25 |
| 13 | Logos Global Management LP | 2.00M (4.18%) | 1.77M Increased by +88.75% | Dec 31, 23 |
| 14 | Vestal Point Capital LP | 2.00M (4.18%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | BRAIDWELL LP | 1.92M (4.01%) | 1.92M Increased by +100.00% | Dec 31, 25 |
| 16 | Lord, Abbett & Co LLC | 1.73M (3.61%) | -587.71K Decreased by -33.98% | Sep 30, 23 |
| 17 | HHG PLC | 1.71M (3.57%) | -59.52K Decreased by -3.49% | Sep 30, 23 |
| 18 | D. E. Shaw & Co LP | 1.67M (3.48%) | 1.14M Increased by +68.62% | Dec 31, 25 |
| 19 | MPM Oncology Impact Management LP | 1.64M (3.43%) | 1.64M Increased by +100.00% | Dec 31, 25 |
| 20 | Holocene Advisors, LP | 1.60M (3.34%) | 61.61K Increased by +3.85% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 2.35M (4.92%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.01M (4.21%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 3 | T. Rowe Price New Horizons | 1.72M (3.60%) | 72.43K Increased by +4.21% | Sep 30, 23 |
| 4 | US Small-Cap Growth II Equity Comp | 1.65M (3.44%) | 1.65M Increased by +100.00% | Jun 30, 23 |
| 5 | BlackRock Event Driven Equity Instl | 1.03M (2.16%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 6 | T. Rowe Price Health Sciences | 784.45K (1.64%) | 784.45K Increased by +100.00% | Sep 30, 23 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 699.62K (1.46%) | 2.17K Increased by +0.31% | Feb 28, 26 |
| 8 | Fidelity Small Cap Index | 621.71K (1.30%) | -23.02K Decreased by -3.70% | May 31, 25 |
| 9 | BlackRock Health Sciences Opps Inv A | 590.65K (1.23%) | -4.42K Decreased by -0.75% | Feb 28, 26 |
| 10 | Janus Henderson Global Life Sciences | 579.04K (1.21%) | -4.52K Decreased by -0.78% | Sep 30, 23 |
| 11 | Janus Henderson Global Life Sciences D | 579.04K (1.21%) | -4.52K Decreased by -0.78% | Sep 30, 23 |
| 12 | Fidelity Series Small Cap Opps | 559.84K (1.17%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 13 | Fidelity® Series Small Cap Opps | 559.84K (1.17%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 14 | iShares Russell 2000 Value ETF | 536.88K (1.12%) | 0.00 Increased by 0.00% | May 31, 25 |
| 15 | Vanguard VIF Small Co Gr | 512.66K (1.07%) | 512.66K Increased by +100.00% | Dec 31, 23 |
| 16 | Pictet-Biotech P USD | 511.48K (1.07%) | 102.70K Increased by +20.08% | Jul 31, 23 |
| 17 | Fidelity Small Cap Growth | 507.80K (1.06%) | -617.00 Decreased by -0.12% | Oct 31, 23 |
| 18 | Fidelity® Small Cap Growth | 507.80K (1.06%) | -617.00 Decreased by -0.12% | Oct 31, 23 |
| 19 | iShares Biotechnology ETF | 481.33K (1.01%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 20 | Fidelity® Small Cap Index | 451.00K (0.94%) | 12.33K Increased by +2.73% | Oct 31, 23 |