| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Suvretta Capital Management, LLC | 6.49M (10.69%) | -974.17K Decreased by -15.01% | Jun 30, 25 |
| 2 | RA Capital Management, LLC | 4.43M (7.30%) | 4.43M Increased by +100.00% | Mar 31, 25 |
| 3 | Acadian Asset Management LLC | 3.39M (5.58%) | 3.39M Increased by +100.00% | Sep 30, 25 |
| 4 | Bvf Inc | 3.35M (5.51%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 5 | Rubric Capital Management LP | 3.34M (5.51%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 6 | Franklin Resources Inc | 2.76M (4.55%) | -71.72K Decreased by -2.60% | Dec 31, 23 |
| 7 | Merck & Co Inc | 2.72M (4.49%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 8 | Verition Fund Managegment, LLC | 2.50M (4.12%) | 555.02K Increased by +22.19% | Sep 30, 23 |
| 9 | Eversept Partners, LLC | 2.29M (3.78%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | MPM Oncology Impact Management LP | 2.16M (3.56%) | -672.00K Decreased by -31.11% | Dec 31, 24 |
| 11 | Holocene Advisors, LP | 2.13M (3.51%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | UBS Group AG | 1.85M (3.04%) | 226.96K Increased by +12.30% | Sep 30, 25 |
| 13 | Parkman Healthcare Partners LLC | 1.73M (2.85%) | 11.79K Increased by +0.68% | Dec 31, 24 |
| 14 | Goldman Sachs Group Inc | 1.71M (2.82%) | -2.31K Decreased by -0.13% | Mar 31, 25 |
| 15 | BlackRock Inc | 1.69M (2.78%) | -419.13K Decreased by -24.83% | Sep 30, 25 |
| 16 | Baillie Gifford & Co Limited. | 1.52M (2.50%) | -329.41K Decreased by -21.68% | Sep 30, 24 |
| 17 | Nuveen Asset Management, LLC | 1.32M (2.18%) | 124.15K Increased by +9.38% | Dec 31, 24 |
| 18 | State Street Corporation | 1.20M (1.97%) | 35.26K Increased by +2.95% | Mar 31, 24 |
| 19 | Aquilo Capital Management, LLC | 1.17M (1.92%) | 744.82K Increased by +63.91% | Mar 31, 24 |
| 20 | Schonfeld Strategic Advisors LLC | 1.12M (1.85%) | 768.10K Increased by +68.39% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 2.42M (3.98%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Franklin Biotechnology Discv A(acc)USD | 1.12M (1.85%) | -56.48K Decreased by -5.02% | Dec 31, 23 |
| 3 | Franklin Small Cap Growth Adv | 963.45K (1.59%) | -5.00K Decreased by -0.52% | Dec 31, 23 |
| 4 | Franklin US Small Cap Growth Equity | 963.45K (1.59%) | -5.00K Decreased by -0.52% | Dec 31, 23 |
| 5 | Baillie Gifford Global Discovery A Acc | 917.84K (1.51%) | 7.41K Increased by +0.81% | Oct 31, 24 |
| 6 | Fidelity Small Cap Index | 835.21K (1.38%) | -23.86K Decreased by -2.86% | May 31, 25 |
| 7 | Edinburgh Worldwide Ord | 750.73K (1.24%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 8 | iShares Russell 2000 Value ETF | 728.08K (1.20%) | 0.00 Increased by 0.00% | May 31, 25 |
| 9 | Fidelity® Small Cap Index | 562.81K (0.93%) | 14.30K Increased by +2.54% | Sep 30, 23 |
| 10 | Belfius Equities Cure C Cap | 550.37K (0.91%) | 0.00 Increased by 0.00% | Feb 29, 24 |
| 11 | Franklin Biotechnology Discovery A | 543.39K (0.90%) | -20.80K Decreased by -3.83% | Dec 31, 23 |
| 12 | State St Russell Sm/Mid Cp® Indx NL Cl C | 502.75K (0.83%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 13 | State St Russell Sm/Mid Cp® Indx SL Cl I | 502.75K (0.83%) | 0.00 Increased by 0.00% | May 31, 25 |
| 14 | Goldman Sachs Small Cp Val Insghts Instl | 467.61K (0.77%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 15 | iShares Biotechnology ETF | 467.05K (0.77%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 16 | Candriam Global Equities Oncology | 440.37K (0.73%) | -110.00K Decreased by -24.98% | Mar 31, 24 |
| 17 | Vanguard Russell 2000 ETF | 409.49K (0.67%) | 3.66K Increased by +0.89% | May 31, 25 |
| 18 | Vanguard US Value Factor ETF | 394.19K (0.65%) | 200.29K Increased by +50.81% | Jun 30, 25 |
| 19 | CREF Stock R1 | 387.49K (0.64%) | -510.05K Decreased by -131.63% | Feb 28, 25 |
| 20 | CREF Stock R3 | 387.49K (0.64%) | -510.05K Decreased by -131.63% | Feb 28, 25 |