| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 36.39M (27.18%) | 2.67M Increased by +7.33% | Dec 31, 25 |
| 2 | FMR Inc | 13.36M (9.98%) | 4.44M Increased by +33.25% | Dec 31, 25 |
| 3 | Vanguard Group Inc | 11.18M (8.35%) | -202.51K Decreased by -1.81% | Dec 31, 25 |
| 4 | State Street Corporation | 8.11M (6.06%) | 5.66M Increased by +69.73% | Mar 31, 24 |
| 5 | BlackRock Inc | 7.36M (5.50%) | 517.13K Increased by +7.02% | Sep 30, 25 |
| 6 | State Street Corp | 6.36M (4.75%) | 2.34M Increased by +36.85% | Sep 30, 25 |
| 7 | T. Rowe Price Associates, Inc. | 4.54M (3.39%) | 633.67K Increased by +13.96% | Sep 30, 25 |
| 8 | Geode Capital Management, LLC | 3.15M (2.35%) | 14.74K Increased by +0.47% | Dec 31, 25 |
| 9 | Citadel Advisors Llc | 2.48M (1.85%) | 2.27M Increased by +91.81% | Dec 31, 25 |
| 10 | Morgan Stanley - Brokerage Accounts | 1.93M (1.44%) | 1.28M Increased by +66.68% | Sep 30, 25 |
| 11 | Balyasny Asset Management LLC | 1.70M (1.27%) | 1.32M Increased by +77.26% | Mar 31, 25 |
| 12 | Polymer Capital Management (Hk) Ltd | 1.42M (1.06%) | 603.88K Increased by +42.49% | Dec 31, 25 |
| 13 | Pictet Asset Manangement SA | 1.38M (1.03%) | -220.39K Decreased by -15.93% | Dec 31, 25 |
| 14 | NORGES BANK | 1.37M (1.03%) | -15.92K Decreased by -1.16% | Dec 31, 25 |
| 15 | APEIRON CAPITAL Ltd | 1.31M (0.98%) | -1.70K Decreased by -0.13% | Dec 31, 25 |
| 16 | abrdn PLC | 1.29M (0.96%) | 154.14K Increased by +11.94% | Dec 31, 24 |
| 17 | UBS Group AG | 1.28M (0.96%) | -815.17K Decreased by -63.75% | Sep 30, 25 |
| 18 | TD Asset Management Inc | 1.21M (0.90%) | 667.74K Increased by +55.40% | Dec 31, 25 |
| 19 | BNP Paribas Arbitrage, SA | 1.10M (0.82%) | 605.30K Increased by +55.10% | Mar 31, 25 |
| 20 | Darwin Global Management, Ltd. | 1.08M (0.81%) | 1.08M Increased by +100.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Health Sciences | 7.03M (5.25%) | -258.44K Decreased by -3.68% | Jan 31, 26 |
| 2 | State Street® SPDR® S&P® Biotech ETF | 4.82M (3.60%) | 26.56K Increased by +0.55% | Feb 28, 26 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 3.55M (2.65%) | 8.39K Increased by +0.24% | Feb 28, 26 |
| 4 | Fidelity Growth Compy Commingled Pl S | 3.06M (2.28%) | 105.74K Increased by +3.46% | Jan 31, 26 |
| 5 | Vanguard Small Cap Index | 2.53M (1.89%) | 5.35K Increased by +0.21% | Feb 28, 26 |
| 6 | SPDR® S&P Biotech ETF | 2.43M (1.81%) | 5.41K Increased by +0.22% | Aug 31, 25 |
| 7 | iShares Russell 2000 ETF | 2.31M (1.73%) | 0.00 Increased by 0.00% | May 31, 25 |
| 8 | Fidelity Growth Company Fund | 2.28M (1.71%) | 61.70K Increased by +2.70% | Jan 31, 26 |
| 9 | Fidelity Select Biotechnology | 1.73M (1.29%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 10 | Vanguard Small Cap Value Index Inv | 1.63M (1.22%) | 4.33K Increased by +0.27% | Feb 28, 26 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 1.63M (1.22%) | 17.71K Increased by +1.09% | Feb 28, 26 |
| 12 | Fidelity® Small Cap Index | 1.12M (0.83%) | 29.95K Increased by +2.69% | Oct 31, 23 |
| 13 | Fidelity Contrafund | 1.04M (0.77%) | -508.93K Decreased by -49.12% | Jan 31, 26 |
| 14 | Fidelity Select Health Care | 1.00M (0.75%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 15 | Polar Capital Biotech S Inc | 1.00M (0.75%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 16 | Fidelity Small Cap Index | 932.02K (0.70%) | 2.56K Increased by +0.28% | May 31, 25 |
| 17 | BlackRock Health Sciences Opps Inv A | 924.15K (0.69%) | -6.92K Decreased by -0.75% | Feb 28, 26 |
| 18 | iShares Russell Mid-Cap Growth ETF | 798.65K (0.60%) | 798.65K Increased by +100.00% | Feb 28, 26 |
| 19 | iShares Biotechnology ETF | 768.83K (0.57%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 20 | Fidelity Extended Market Index | 765.10K (0.57%) | -18.43K Decreased by -2.41% | Jan 31, 26 |