| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 11.81M (13.32%) | 352.89K Increased by +2.99% | Sep 30, 25 |
| 2 | Vanguard Group Inc | 7.96M (8.98%) | 1.33M Increased by +16.75% | Dec 31, 25 |
| 3 | Suvretta Capital Management, LLC | 5.19M (5.85%) | 1.50M Increased by +28.91% | Dec 31, 25 |
| 4 | Wellington Management Company LLP | 5.18M (5.85%) | 3.92M Increased by +75.58% | Dec 31, 25 |
| 5 | State Street Corporation | 4.90M (5.53%) | 664.94K Increased by +13.56% | Mar 31, 24 |
| 6 | Woodline Partners LP | 3.77M (4.25%) | 104.00 Increased by +0.00% | Dec 31, 25 |
| 7 | State Street Corp | 3.39M (3.83%) | -235.96K Decreased by -6.95% | Sep 30, 25 |
| 8 | Marshall Wace Asset Management Ltd | 3.39M (3.82%) | 3.39M Increased by +100.00% | Dec 31, 25 |
| 9 | Point72 Asset Management, L.P. | 3.28M (3.70%) | -1.05M Decreased by -32.09% | Dec 31, 25 |
| 10 | Siren, L.L.C. | 3.01M (3.39%) | 95.00K Increased by +3.16% | Dec 31, 25 |
| 11 | Octagon Capital Advisors LP | 1.97M (2.22%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | Fisher Asset Management, LLC | 1.95M (2.20%) | 1.22M Increased by +62.60% | Dec 31, 25 |
| 13 | Geode Capital Management, LLC | 1.91M (2.15%) | 308.94K Increased by +16.20% | Dec 31, 25 |
| 14 | Invus Financial Advisors, LLC | 1.61M (1.82%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 15 | Samlyn Capital, LLC | 1.60M (1.81%) | 1.60M Increased by +100.00% | Dec 31, 25 |
| 16 | Boxer Capital LLC | 1.60M (1.81%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 17 | Boxer Capital Management, LLC | 1.60M (1.81%) | 1.60M Increased by +100.00% | Dec 31, 24 |
| 18 | Ameriprise Financial Inc | 1.55M (1.75%) | 228.32K Increased by +14.75% | Dec 31, 24 |
| 19 | Morgan Stanley - Brokerage Accounts | 1.54M (1.73%) | 66.28K Increased by +4.32% | Sep 30, 25 |
| 20 | Dimensional Fund Advisors, Inc. | 1.52M (1.72%) | 21.69K Increased by +1.42% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | iShares Core S&P Small-Cap ETF | 5.19M (5.85%) | 1.57M Increased by +30.30% | Feb 28, 26 |
| 2 | Vanguard Health Care Inv | 3.21M (3.62%) | 3.21M Increased by +100.00% | Dec 31, 25 |
| 3 | Fidelity® Select Biotechnology | 2.94M (3.31%) | -256.50K Decreased by -8.73% | Nov 30, 23 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 2.52M (2.84%) | 7.99K Increased by +0.32% | Feb 28, 26 |
| 5 | iShares Russell 2000 ETF | 1.91M (2.16%) | 797.43K Increased by +41.67% | Feb 28, 26 |
| 6 | Vanguard US Total Market Shares ETF | 1.62M (1.82%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | State Street® SPDR® S&P® Biotech ETF | 1.55M (1.74%) | 8.58K Increased by +0.55% | Feb 28, 26 |
| 8 | SPDR® S&P Biotech ETF | 1.20M (1.36%) | 2.69K Increased by +0.22% | Aug 31, 25 |
| 9 | Fidelity Select Health Care | 949.76K (1.07%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | BNP Paribas US Small Cap ClassicC | 947.31K (1.07%) | 947.31K Increased by +100.00% | Jan 31, 26 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 932.09K (1.05%) | 5.92K Increased by +0.63% | Feb 28, 26 |
| 12 | Belfius Equities Cure C Cap | 926.12K (1.04%) | 0.00 Increased by 0.00% | Nov 30, 25 |
| 13 | CT (Lux) American Smaller Com 9U USD | 906.88K (1.02%) | 55.03K Increased by +6.07% | Jan 31, 25 |
| 14 | Vanguard Small Cap Index | 893.53K (1.01%) | 1.91K Increased by +0.21% | Feb 28, 26 |
| 15 | Fidelity Select Pharmaceuticals Port | 853.52K (0.96%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 16 | Fidelity Select Biotechnology | 824.30K (0.93%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 17 | State Street SPDR Port S&P 600 Sm CpETF | 796.17K (0.90%) | 2.19K Increased by +0.28% | Feb 27, 26 |
| 18 | BNP Paribas US Small Cap Classic R | 776.48K (0.88%) | -15.64K Decreased by -2.01% | May 31, 25 |
| 19 | Fidelity Small Cap Index | 771.08K (0.87%) | 74.45K Increased by +9.66% | Dec 31, 25 |
| 20 | BGF World Healthscience A2 | 616.09K (0.69%) | 0.00 Increased by 0.00% | Nov 30, 25 |