| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 6.24M (12.69%) | 181.36K Increased by +2.91% | Dec 31, 25 |
| 2 | venBio Select Advisor LLC | 6.15M (12.50%) | 1.71M Increased by +27.73% | Dec 31, 25 |
| 3 | EcoR1 Capital, LLC | 3.99M (8.11%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | RTW INVESTMENTS, LLC | 3.71M (7.55%) | -713.51K Decreased by -19.22% | Dec 31, 25 |
| 5 | Vestal Point Capital LP | 3.70M (7.52%) | -1.09M Decreased by -29.53% | Jun 30, 25 |
| 6 | Aberdeen Group PLC | 3.68M (7.48%) | 738.90K Increased by +20.09% | Dec 31, 25 |
| 7 | State Street Corporation | 3.48M (7.07%) | 28.59K Increased by +0.82% | Dec 31, 23 |
| 8 | JPMorgan Chase & Co | 2.30M (4.67%) | 491.02K Increased by +21.36% | Sep 30, 25 |
| 9 | Boxer Capital LLC | 2.23M (4.52%) | 2.23M Increased by +100.00% | Sep 30, 24 |
| 10 | Jefferies Financial Group Inc | 2.10M (4.26%) | 2.10M Increased by +100.00% | Jun 30, 25 |
| 11 | Franklin Resources Inc | 1.99M (4.04%) | 383.07K Increased by +19.26% | Sep 30, 25 |
| 12 | Point72 Asset Management, L.P. | 1.77M (3.60%) | 794.46K Increased by +44.85% | Dec 31, 24 |
| 13 | Sofinnova Ventures | 1.56M (3.17%) | 1.01M Increased by +64.98% | Jun 30, 25 |
| 14 | abrdn PLC | 1.51M (3.07%) | -419.73K Decreased by -27.81% | Dec 31, 24 |
| 15 | Two Sigma Investments LLC | 1.45M (2.95%) | 553.75K Increased by +38.16% | Dec 31, 25 |
| 16 | BlackRock Inc | 1.45M (2.94%) | 112.44K Increased by +7.78% | Sep 30, 25 |
| 17 | State Street Corp | 1.44M (2.94%) | 301.20K Increased by +20.86% | Sep 30, 25 |
| 18 | Goldman Sachs Group Inc | 1.39M (2.83%) | 928.87K Increased by +66.79% | Dec 31, 23 |
| 19 | MPM Oncology Impact Management LP | 1.38M (2.81%) | 1.38M Increased by +100.00% | Dec 31, 25 |
| 20 | Jennison Associates LLC | 1.37M (2.79%) | 371.71K Increased by +27.11% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | State Street® SPDR® S&P® Biotech ETF | 2.76M (5.62%) | 15.22K Increased by +0.55% | Feb 28, 26 |
| 2 | abrdn Healthcare Investors | 1.62M (3.29%) | 100.44K Increased by +6.21% | Feb 28, 26 |
| 3 | RTW Biotech Opportunities Ord | 1.39M (2.82%) | 1.39M Increased by +100.00% | Jun 30, 25 |
| 4 | Fidelity Advisor Biotechnology I | 991.60K (2.02%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 5 | abrdn World Healthcare | 987.82K (2.01%) | 48.33K Increased by +4.89% | Jan 31, 26 |
| 6 | Fidelity Select Pharmaceuticals Port | 960.38K (1.95%) | 41.59K Increased by +4.33% | Jan 31, 26 |
| 7 | SPDR® S&P Biotech ETF | 838.29K (1.70%) | 1.87K Increased by +0.22% | Aug 31, 25 |
| 8 | abrdn Life Sciences Investors | 743.19K (1.51%) | 48.47K Increased by +6.52% | Feb 28, 26 |
| 9 | Delaware Healthcare I | 706.17K (1.44%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | Macquarie Healthcare I | 706.17K (1.44%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 680.91K (1.38%) | 7.36K Increased by +1.08% | Feb 28, 26 |
| 12 | Fidelity Select Health Care | 670.00K (1.36%) | -230.00K Decreased by -34.33% | Jan 31, 26 |
| 13 | Fidelity Select Biotechnology | 650.28K (1.32%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 14 | Biotech Growth Ord | 618.55K (1.26%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 15 | JPMorgan Growth Advantage A | 570.59K (1.16%) | -15.49K Decreased by -2.71% | Jan 31, 26 |
| 16 | JPM US Mid Cap Growth-Composite | 568.85K (1.16%) | 568.85K Increased by +100.00% | Dec 31, 25 |
| 17 | Franklin Biotechnology Discovery A | 568.80K (1.16%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 18 | JPMorgan Mid Cap Growth I | 566.80K (1.15%) | -2.05K Decreased by -0.36% | Jan 31, 26 |
| 19 | Strategic Advisers Fidelity US TtlStk | 563.80K (1.15%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 20 | MEDICAL BioHealth EUR Acc | 554.36K (1.13%) | 119.24K Increased by +21.51% | Jun 30, 25 |