| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Deerfield Management Co | 17.99M (40.13%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | FMR Inc | 9.97M (22.24%) | 31.65K Increased by +0.32% | Jun 30, 25 |
| 3 | Paradigm Biocapital Advisors LP | 5.27M (11.75%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | Vanguard Group Inc | 4.52M (10.09%) | 84.29K Increased by +1.86% | Jun 30, 25 |
| 5 | BlackRock Inc | 4.05M (9.03%) | 297.89K Increased by +7.36% | Jun 30, 25 |
| 6 | T. Rowe Price Associates, Inc. | 1.80M (4.01%) | 344.77K Increased by +19.20% | Jun 30, 25 |
| 7 | HHG PLC | 1.78M (3.98%) | 472.38K Increased by +26.50% | Jun 30, 25 |
| 8 | State Street Corporation | 1.70M (3.80%) | 440.77K Increased by +25.91% | Dec 31, 23 |
| 9 | Wellington Management Company LLP | 1.58M (3.52%) | 133.99K Increased by +8.50% | Jun 30, 25 |
| 10 | State Street Corp | 1.49M (3.32%) | 59.62K Increased by +4.00% | Jun 30, 25 |
| 11 | Bain Capital Life Sciences Investors, LLC | 1.45M (3.23%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | Perceptive Advisors LLC | 1.38M (3.07%) | -258.79K Decreased by -18.82% | Jun 30, 25 |
| 13 | COMMODORE CAPITAL LP | 1.38M (3.07%) | -480.00K Decreased by -34.91% | Jun 30, 25 |
| 14 | JPMorgan Chase & Co | 1.20M (2.67%) | 1.10M Increased by +91.48% | Jun 30, 25 |
| 15 | BRAIDWELL LP | 1.18M (2.62%) | 334.93K Increased by +28.48% | Jun 30, 25 |
| 16 | Boxer Capital LLC | 1.12M (2.50%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 17 | Boxer Capital Management, LLC | 1.12M (2.50%) | 1.12M Increased by +100.00% | Dec 31, 24 |
| 18 | T. Rowe Price Investment Management,Inc. | 1.09M (2.44%) | 643.79K Increased by +58.82% | Jun 30, 25 |
| 19 | Vestal Point Capital LP | 1.07M (2.40%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | Geode Capital Management, LLC | 996.85K (2.22%) | 103.39K Increased by +10.37% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl O | 2.48M (5.52%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 2 | Fidelity Growth Compy Commingled Pl S | 2.44M (5.44%) | 3.17K Increased by +0.13% | Jul 31, 25 |
| 3 | Fidelity Growth Company Fund | 1.72M (3.83%) | -10.27K Decreased by -0.60% | Jul 31, 25 |
| 4 | Fidelity® Growth Company | 1.60M (3.57%) | 36.30K Increased by +2.27% | Nov 30, 23 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 1.46M (3.27%) | -31.09K Decreased by -2.12% | Jul 31, 25 |
| 6 | Vanguard Small Cap Index | 1.13M (2.52%) | -7.43K Decreased by -0.66% | Jul 31, 25 |
| 7 | iShares Russell 2000 ETF | 1.04M (2.31%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 8 | Vanguard Small Cap Value Index Inv | 727.18K (1.62%) | 2.80K Increased by +0.38% | Jul 31, 25 |
| 9 | Fidelity Select Health Care | 701.80K (1.57%) | 1.80K Increased by +0.26% | Jul 31, 25 |
| 10 | JPMorgan Mid Cap Growth I | 649.87K (1.45%) | 196.81K Increased by +30.28% | Jul 31, 25 |
| 11 | Polar Capital Biotech S Inc | 625.00K (1.39%) | 205.00K Increased by +32.80% | Jul 31, 25 |
| 12 | Fidelity® Growth Company K6 | 617.41K (1.38%) | 540.00 Increased by +0.09% | Nov 30, 23 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 593.56K (1.32%) | 2.17K Increased by +0.37% | Jun 30, 25 |
| 14 | SPDR® S&P Biotech ETF | 590.59K (1.32%) | 1.31K Increased by +0.22% | Aug 31, 25 |
| 15 | Fidelity® Small Cap Growth | 549.27K (1.23%) | -667.00 Decreased by -0.12% | Oct 31, 23 |
| 16 | Vanguard Health Care Inv | 534.47K (1.19%) | 144.97K Increased by +27.12% | Jun 30, 25 |
| 17 | Fidelity Growth Company K6 | 525.41K (1.17%) | 7.13K Increased by +1.36% | Jul 31, 25 |
| 18 | US Small-Cap Growth II Equity Comp | 516.87K (1.15%) | 47.62K Increased by +9.21% | Jun 30, 25 |
| 19 | Fidelity Small Cap Growth | 512.71K (1.14%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | T. Rowe Price New Horizons | 498.00K (1.11%) | -18.87K Decreased by -3.79% | Jul 31, 25 |