| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Cormorant Asset Management, LLC | 8.27M (14.34%) | -60.00K Decreased by -0.73% | Dec 31, 25 |
| 2 | Suvretta Capital Management, LLC | 7.83M (13.58%) | 1.63M Increased by +20.89% | Dec 31, 25 |
| 3 | BlackRock Inc | 4.96M (8.61%) | -395.69K Decreased by -7.97% | Sep 30, 25 |
| 4 | Vanguard Group Inc | 4.82M (8.37%) | 1.03M Increased by +21.31% | Dec 31, 25 |
| 5 | Adage Capital Partners Gp LLC | 4.70M (8.15%) | -859.78K Decreased by -18.29% | Dec 31, 25 |
| 6 | Federated Hermes Inc | 4.42M (7.66%) | -183.12K Decreased by -4.15% | Sep 30, 25 |
| 7 | Franklin Resources Inc | 4.17M (7.24%) | -129.24K Decreased by -3.10% | Sep 30, 25 |
| 8 | Paradigm Biocapital Advisors LP | 3.69M (6.40%) | 1.69M Increased by +45.68% | Dec 31, 25 |
| 9 | TCG Crossover Management, LLC | 3.57M (6.20%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 10 | RA Capital Management, LLC | 3.18M (5.52%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | Orbimed Advisors, LLC | 2.47M (4.28%) | 672.31K Increased by +27.24% | Dec 31, 25 |
| 12 | Citadel Advisors Llc | 2.14M (3.70%) | -208.82K Decreased by -9.78% | Sep 30, 25 |
| 13 | Millennium Management LLC | 2.05M (3.55%) | 917.80K Increased by +44.85% | Mar 31, 24 |
| 14 | Geode Capital Management, LLC | 1.90M (3.29%) | 374.84K Increased by +19.74% | Dec 31, 25 |
| 15 | Aberdeen Group PLC | 1.61M (2.79%) | 809.18K Increased by +50.39% | Dec 31, 25 |
| 16 | Perceptive Advisors LLC | 1.54M (2.67%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | The Goldman Sachs Group Inc | 1.51M (2.63%) | 233.91K Increased by +15.44% | Sep 30, 25 |
| 18 | State Street Corp | 1.47M (2.56%) | -42.35K Decreased by -2.87% | Sep 30, 25 |
| 19 | T. Rowe Price Associates, Inc. | 1.35M (2.35%) | -790.73K Decreased by -58.40% | Mar 31, 25 |
| 20 | Patient Square Capital | 1.35M (2.35%) | -129.14K Decreased by -9.55% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Federated Hermes Kaufmann Growth | 2.77M (4.81%) | 733.00K Increased by +26.45% | Dec 31, 25 |
| 2 | Federated Hermes Kaufmann R | 2.77M (4.81%) | 733.00K Increased by +26.45% | Dec 31, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 2.60M (4.51%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 4 | Franklin Biotechnology Discv A(acc)USD | 2.19M (3.80%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 5 | Federated Hermes Kaufmann Small Cap A | 1.98M (3.44%) | 497.00K Increased by +25.08% | Dec 31, 25 |
| 6 | Federated Hermes Kaufmann Small Cap Grow | 1.98M (3.44%) | 497.00K Increased by +25.08% | Dec 31, 25 |
| 7 | iShares Russell 2000 ETF | 1.83M (3.18%) | 1.31M Increased by +71.51% | Feb 28, 26 |
| 8 | Vanguard US Total Market Shares ETF | 1.56M (2.70%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 9 | Franklin Small Cap Growth Adv | 1.36M (2.35%) | 75.17K Increased by +5.54% | Feb 28, 26 |
| 10 | Franklin US Small Cap Growth Equity | 1.28M (2.22%) | 110.25K Increased by +8.60% | Dec 31, 25 |
| 11 | Franklin Biotechnology Discovery A | 1.27M (2.20%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 12 | Franklin Small Cap Growth SMA | 1.27M (2.20%) | 1.27M Increased by +99.99% | Jun 30, 25 |
| 13 | abrdn Healthcare Investors | 1.21M (2.10%) | 143.01K Increased by +11.80% | Feb 28, 26 |
| 14 | T. Rowe Price New Horizons | 900.54K (1.56%) | -248.79K Decreased by -27.63% | Mar 31, 25 |
| 15 | US Small-Cap Growth II Equity Comp | 900.54K (1.56%) | -249.12K Decreased by -27.66% | Mar 31, 25 |
| 16 | Biotech Growth Ord | 881.30K (1.53%) | 0.00 Increased by 0.00% | Nov 30, 25 |
| 17 | Vanguard Institutional Extnd Mkt Idx Tr | 852.03K (1.48%) | 9.70K Increased by +1.14% | Feb 28, 26 |
| 18 | Fidelity Small Cap Index | 741.57K (1.29%) | 147.18K Increased by +19.85% | Dec 31, 25 |
| 19 | HSBC GIF Glb Eq Sust Hlthcare AC USD | 701.13K (1.22%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 20 | Columbia Small Cap Growth | 693.23K (1.20%) | 251.24K Increased by +36.24% | Jun 30, 24 |