| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Investment Management,Inc. | 20.33M (9.95%) | 3.04M Increased by +14.95% | Jun 30, 25 |
| 2 | VR Adviser, LLC | 17.86M (8.74%) | 1.64M Increased by +9.19% | Jun 30, 25 |
| 3 | BlackRock Inc | 15.17M (7.42%) | -432.61K Decreased by -2.85% | Jun 30, 25 |
| 4 | Logos Global Management LP | 15.00M (7.34%) | 2.00M Increased by +13.33% | Jun 30, 25 |
| 5 | Suvretta Capital Management, LLC | 14.50M (7.10%) | 2.19M Increased by +15.08% | Jun 30, 25 |
| 6 | Vanguard Group Inc | 12.70M (6.21%) | -31.83K Decreased by -0.25% | Jun 30, 25 |
| 7 | Paradigm Biocapital Advisors LP | 11.91M (5.83%) | 1.10M Increased by +9.28% | Jun 30, 25 |
| 8 | ARCH VENTURE CORP | 11.06M (5.41%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | Cormorant Asset Management, LLC | 10.81M (5.29%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 10 | Siren, L.L.C. | 8.76M (4.29%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 11 | Vivo Capital, LLC | 6.76M (3.31%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | Armistice Capital, LLC | 6.17M (3.02%) | -1.92M Decreased by -31.17% | Mar 31, 24 |
| 13 | 5AM Venture Management, LLC | 5.41M (2.65%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 14 | Octagon Capital Advisors LP | 5.14M (2.51%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 15 | Geode Capital Management, LLC | 4.84M (2.37%) | 77.79K Increased by +1.61% | Jun 30, 25 |
| 16 | Artal Group S A | 4.72M (2.31%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 17 | Citadel Advisors Llc | 4.29M (2.10%) | -27.30K Decreased by -0.64% | Dec 31, 24 |
| 18 | HHG PLC | 4.11M (2.01%) | -4.07M Decreased by -99.00% | Sep 30, 24 |
| 19 | Affinity Asset Advisors, LLC | 4.09M (2.00%) | 744.27K Increased by +18.22% | Jun 30, 25 |
| 20 | State Street Corp | 4.00M (1.96%) | -175.78K Decreased by -4.39% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 7.33M (3.59%) | -162.46K Decreased by -2.22% | Jul 31, 25 |
| 2 | T. Rowe Price Small-Cap Value | 5.94M (2.91%) | -178.14K Decreased by -3.00% | Jul 31, 25 |
| 3 | iShares Russell 2000 ETF | 4.23M (2.07%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 4 | T. Rowe Price U.S. SC Value Eq Tr-D | 3.95M (1.93%) | 1.03M Increased by +26.16% | Jun 30, 25 |
| 5 | T. Rowe Price US Small-Cap Core Equity | 3.57M (1.75%) | -6.46K Decreased by -0.18% | Jun 30, 25 |
| 6 | T. Rowe Price Small-Cap Stock | 3.57M (1.75%) | -2.88K Decreased by -0.08% | Jul 31, 25 |
| 7 | T. Rowe Price U.S. SC Value Eq Tr-Z | 2.91M (1.43%) | 147.12K Increased by +5.05% | Mar 31, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 2.29M (1.12%) | -981.29K Decreased by -42.89% | Jul 31, 25 |
| 9 | SPDR® S&P Biotech ETF | 2.23M (1.09%) | -13.57K Decreased by -0.61% | Feb 28, 25 |
| 10 | International Biotechnology Ord | 1.93M (0.94%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 11 | T. Rowe Price Instl Small-Cap Stock | 1.85M (0.91%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | T. Rowe Price U.S. SC Core Eq Tr-D | 1.83M (0.89%) | 6.46K Increased by +0.35% | Jun 30, 25 |
| 13 | T. Rowe Price U.S. SC Core Eq Tr-Z | 1.82M (0.89%) | 27.83K Increased by +1.53% | Mar 31, 25 |
| 14 | Fidelity Small Cap Index | 1.76M (0.86%) | -128.09K Decreased by -7.29% | Jun 30, 25 |
| 15 | T. Rowe Price US Smlr Coms Eq A | 1.58M (0.77%) | -20.24K Decreased by -1.28% | Jul 31, 25 |
| 16 | iShares Russell 2000 Value ETF | 1.56M (0.76%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 17 | T. Rowe Price US Smlr Cm Eq A USD | 1.35M (0.66%) | -69.10K Decreased by -5.13% | Apr 30, 25 |
| 18 | Fidelity Extended Market Index | 1.16M (0.57%) | -9.55K Decreased by -0.82% | Jul 31, 25 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 1.10M (0.54%) | 5.90K Increased by +0.54% | Apr 30, 25 |
| 20 | State St Russell Sm/Mid Cp® Indx SL Cl I | 1.10M (0.54%) | 0.00 Increased by 0.00% | Jul 31, 25 |