| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 9.71M (7.24%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | HHG PLC | 9.44M (7.03%) | -915.45K Decreased by -9.70% | Jun 30, 25 |
| 3 | BlackRock Inc | 8.08M (6.02%) | 31.49K Increased by +0.39% | Jun 30, 25 |
| 4 | Vanguard Group Inc | 7.65M (5.70%) | 244.81K Increased by +3.20% | Jun 30, 25 |
| 5 | FCPM III SERVICES BV | 5.46M (4.07%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | FMR Inc | 5.29M (3.94%) | 98.08K Increased by +1.85% | Jun 30, 25 |
| 7 | Siren, L.L.C. | 4.84M (3.60%) | 2.12M Increased by +43.80% | Jun 30, 25 |
| 8 | State Street Corporation | 4.19M (3.12%) | 1.86M Increased by +44.27% | Mar 31, 24 |
| 9 | TCG Crossover Management, LLC | 3.77M (2.81%) | 1.12M Increased by +29.64% | Jun 30, 25 |
| 10 | State Street Corp | 3.36M (2.50%) | -253.97K Decreased by -7.57% | Jun 30, 25 |
| 11 | BRAIDWELL LP | 3.27M (2.44%) | -348.00K Decreased by -10.63% | Jun 30, 25 |
| 12 | Adage Capital Partners Gp LLC | 3.19M (2.38%) | 3.19M Increased by +100.00% | Jun 30, 25 |
| 13 | JPMorgan Chase & Co | 3.09M (2.30%) | 555.47K Increased by +18.00% | Jun 30, 25 |
| 14 | Citadel Advisors Llc | 3.01M (2.24%) | 147.81K Increased by +4.91% | Mar 31, 25 |
| 15 | Armistice Capital, LLC | 2.56M (1.91%) | -208.00K Decreased by -8.13% | Jun 30, 25 |
| 16 | T. Rowe Price Associates, Inc. | 2.38M (1.78%) | 563.54K Increased by +23.64% | Jun 30, 25 |
| 17 | Holocene Advisors, LP | 2.35M (1.75%) | 365.52K Increased by +15.57% | Dec 31, 24 |
| 18 | Geode Capital Management, LLC | 2.25M (1.68%) | 298.17K Increased by +13.23% | Jun 30, 25 |
| 19 | Perceptive Advisors LLC | 2.25M (1.67%) | -66.01K Decreased by -2.94% | Jun 30, 25 |
| 20 | VR Adviser, LLC | 2.17M (1.62%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.90M (2.91%) | 827.02K Increased by +21.18% | Jul 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.65M (1.98%) | 2.40K Increased by +0.09% | Sep 30, 24 |
| 3 | Janus Henderson Glb Life Scn I2 USD | 2.40M (1.79%) | 844.64K Increased by +35.21% | Jul 31, 25 |
| 4 | iShares Russell 2000 ETF | 2.27M (1.69%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 5 | JPMorgan Small Cap Growth A | 1.94M (1.45%) | 496.51K Increased by +25.56% | Jul 31, 25 |
| 6 | Janus Henderson Global Life Sciences | 1.89M (1.41%) | 124.72K Increased by +6.61% | Jun 30, 25 |
| 7 | Janus Henderson Global Life Sciences D | 1.89M (1.41%) | 80.26K Increased by +4.25% | Jun 30, 25 |
| 8 | Fidelity Growth Compy Commingled Pl S | 1.84M (1.37%) | 2.39K Increased by +0.13% | Jul 31, 25 |
| 9 | Fidelity Growth Compy Commingled Pl O | 1.79M (1.33%) | 348.61K Increased by +19.51% | Aug 31, 24 |
| 10 | Fidelity Select Biotechnology | 1.61M (1.20%) | 82.40K Increased by +5.12% | Jul 31, 25 |
| 11 | Janus Global Life Science AUSD | 1.55M (1.16%) | 121.81K Increased by +7.84% | Jun 30, 25 |
| 12 | Vanguard Small Cap Index | 1.51M (1.12%) | 326.28K Increased by +21.66% | Jul 31, 25 |
| 13 | SPDR® S&P Biotech ETF | 1.34M (1.00%) | 3.00K Increased by +0.22% | Aug 31, 25 |
| 14 | Fidelity Growth Company Fund | 1.29M (0.96%) | -7.74K Decreased by -0.60% | Jul 31, 25 |
| 15 | T. Rowe Price Small-Cap Value | 1.26M (0.94%) | 254.72K Increased by +20.16% | Jul 31, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 1.21M (0.90%) | -176.12K Decreased by -14.50% | Jul 31, 25 |
| 17 | US Small-Cap Growth II Equity Comp | 1.12M (0.83%) | 219.42K Increased by +19.60% | Jun 30, 25 |
| 18 | RTW Biotech Opportunities Ord | 1.11M (0.83%) | 1.11M Increased by +100.00% | Jun 30, 24 |
| 19 | Vanguard Small Cap Value Index Inv | 972.38K (0.72%) | 219.19K Increased by +22.54% | Jul 31, 25 |
| 20 | Fidelity Small Cap Index | 941.76K (0.70%) | 94.52K Increased by +10.04% | Jun 30, 25 |