| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Orbimed Advisors, LLC | 7.17M (9.92%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | BlackRock Inc | 4.71M (6.52%) | 472.03K Increased by +10.02% | Sep 30, 25 |
| 3 | Samlyn Capital, LLC | 4.07M (5.63%) | -2.60M Decreased by -63.97% | Mar 31, 25 |
| 4 | Vanguard Group Inc | 3.87M (5.36%) | 401.56K Increased by +10.37% | Dec 31, 25 |
| 5 | Adams Street Partners LLC | 3.28M (4.54%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 6 | Point72 Asset Management, L.P. | 2.88M (3.98%) | -3.58M Decreased by -124.50% | Dec 31, 25 |
| 7 | MPM Oncology Impact Management LP | 2.74M (3.80%) | 2.74M Increased by +100.00% | Dec 31, 25 |
| 8 | Vivo Capital, LLC | 2.23M (3.09%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 9 | Geode Capital Management, LLC | 1.47M (2.04%) | 16.50K Increased by +1.12% | Dec 31, 25 |
| 10 | Perceptive Advisors LLC | 1.44M (1.99%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 11 | Foresite Capital Management VI LLC | 1.38M (1.91%) | -350.00K Decreased by -25.34% | Dec 31, 25 |
| 12 | State Street Corp | 1.01M (1.39%) | 341.55K Increased by +33.94% | Sep 30, 25 |
| 13 | Deerfield Management Co | 1.00M (1.38%) | 1.00M Increased by +100.00% | Dec 31, 24 |
| 14 | Susquehanna International Group, LLP | 951.34K (1.32%) | -63.74K Decreased by -6.70% | Mar 31, 25 |
| 15 | DCF Advisers, LLC | 729.00K (1.01%) | -39.50K Decreased by -5.42% | Dec 31, 25 |
| 16 | Millennium Management LLC | 688.77K (0.95%) | 688.77K Increased by +100.00% | Dec 31, 25 |
| 17 | Morgan Stanley - Brokerage Accounts | 617.22K (0.85%) | -277.18K Decreased by -44.91% | Sep 30, 25 |
| 18 | Ghost Tree Capital, LLC | 500.00K (0.69%) | 500.00K Increased by +100.00% | Sep 30, 24 |
| 19 | Logos Global Management LP | 500.00K (0.69%) | 500.00K Increased by +100.00% | Dec 31, 25 |
| 20 | Northern Trust Corp | 466.49K (0.65%) | 63.34K Increased by +13.58% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.34M (3.24%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 2 | State Street® SPDR® S&P® Biotech ETF | 1.66M (2.30%) | 9.20K Increased by +0.55% | Feb 28, 26 |
| 3 | Vanguard US Total Market Shares ETF | 1.58M (2.19%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 1.39M (1.93%) | 1.39M Increased by +100.00% | Feb 28, 26 |
| 5 | Polar Capital Healthcare Opports Inc | 830.54K (1.15%) | 830.54K Increased by +100.00% | Jan 31, 26 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 793.66K (1.10%) | 8.61K Increased by +1.08% | Feb 28, 26 |
| 7 | MEDICAL BioHealth EUR Acc | 739.50K (1.02%) | 739.50K Increased by +100.00% | Jan 31, 26 |
| 8 | Fidelity Small Cap Index | 563.65K (0.78%) | -38.68K Decreased by -6.86% | Dec 31, 25 |
| 9 | iShares Russell 2000 Growth ETF | 477.48K (0.66%) | 477.48K Increased by +100.00% | Feb 28, 26 |
| 10 | iShares Biotechnology ETF | 473.30K (0.66%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 11 | T. Rowe Price New Horizons | 404.05K (0.56%) | 404.05K Increased by +100.00% | Jan 31, 26 |
| 12 | Fidelity Extended Market Index | 379.02K (0.52%) | 33.26K Increased by +8.77% | Jan 31, 26 |
| 13 | State St Russell Sm/Mid Cp® Indx SL Cl I | 333.64K (0.46%) | 17.00K Increased by +5.10% | Feb 28, 26 |
| 14 | Vanguard Russell 2000 ETF | 283.62K (0.39%) | 11.07K Increased by +3.90% | Feb 28, 26 |
| 15 | SEB Läkemedelsfond | 226.84K (0.31%) | 226.84K Increased by +100.00% | Jan 31, 26 |
| 16 | Polar Capital Glb Healthcare Ord | 196.03K (0.27%) | 196.03K Increased by +100.00% | Jan 31, 26 |
| 17 | State St Russell Sm Cap® Indx SL Cl I | 188.40K (0.26%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 18 | Blackrock Extended Mkt Fund CF | 181.53K (0.25%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 19 | Fidelity® Extended Market Index | 178.09K (0.25%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | Vanguard Health Care ETF | 167.79K (0.23%) | -915.00 Decreased by -0.55% | Feb 28, 26 |