| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 10.28M (16.89%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | Westfield Capital Management Company, L.P. | 5.19M (8.52%) | -74.21K Decreased by -1.43% | Dec 31, 25 |
| 3 | Westfield Capital Management Company, LP | 5.13M (8.43%) | 170.94K Increased by +3.33% | Sep 30, 24 |
| 4 | venBio Select Advisor LLC | 5.11M (8.40%) | 1.11K Increased by +0.02% | Dec 31, 25 |
| 5 | HHG PLC | 4.32M (7.10%) | -104.73K Decreased by -2.42% | Sep 30, 25 |
| 6 | Lombard Odier Asset Management (Europe) Ltd | 4.27M (7.01%) | 4.27M Increased by +100.00% | Sep 30, 25 |
| 7 | FMR Inc | 4.15M (6.82%) | -318.42K Decreased by -7.67% | Dec 31, 25 |
| 8 | Artisan Partners Limited Partnership | 3.23M (5.30%) | -495.00K Decreased by -15.34% | Dec 31, 25 |
| 9 | Capital Research & Mgmt Co - Division 3 | 3.06M (5.03%) | 3.33K Increased by +0.11% | Dec 31, 25 |
| 10 | T. Rowe Price Investment Management,Inc. | 2.75M (4.51%) | 81.23K Increased by +2.96% | Dec 31, 25 |
| 11 | Morgan Stanley - Brokerage Accounts | 1.90M (3.13%) | 1.08M Increased by +56.62% | Mar 31, 25 |
| 12 | Massachusetts Financial Services Company | 1.89M (3.10%) | 3.61K Increased by +0.19% | Dec 31, 25 |
| 13 | Wellington Management Company LLP | 1.76M (2.90%) | -36.21K Decreased by -2.05% | Dec 31, 25 |
| 14 | T. Rowe Price Associates, Inc. | 1.73M (2.84%) | -149.26K Decreased by -8.65% | Sep 30, 25 |
| 15 | Franklin Resources Inc | 1.59M (2.61%) | -163.51K Decreased by -10.28% | Sep 30, 25 |
| 16 | American Century Companies Inc | 1.44M (2.37%) | 898.53K Increased by +62.26% | Dec 31, 25 |
| 17 | Perceptive Advisors LLC | 1.09M (1.79%) | 124.61K Increased by +11.45% | Sep 30, 25 |
| 18 | Amvescap Plc. | 917.90K (1.51%) | -29.32K Decreased by -3.19% | Sep 30, 25 |
| 19 | Polar Capital Holdings PLC | 857.91K (1.41%) | 20.13K Increased by +2.35% | Sep 30, 25 |
| 20 | Adage Capital Partners Gp LLC | 820.51K (1.35%) | 611.00K Increased by +74.47% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | TimesSquare CIT Mid Cap Growth A | 9.14M (15.01%) | 9.09M Increased by +99.45% | Dec 31, 23 |
| 2 | MFS Mid Cap Growth A | 1.28M (2.10%) | 722.55K Increased by +56.46% | Jan 31, 26 |
| 3 | MFS Mid Cap Growth Equity | 1.28M (2.10%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 4 | American Funds Growth Fund of Amer A | 1.21M (1.99%) | 147.54K Increased by +12.20% | Dec 31, 25 |
| 5 | Capital Group Growth Fnd of Amer Comp | 1.21M (1.99%) | 147.54K Increased by +12.20% | Dec 31, 25 |
| 6 | Vanguard Health Care Inv | 1.10M (1.81%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 7 | Franklin DynaTech Fund A | 1.00M (1.64%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 8 | Franklin Innovation Composite | 1.00M (1.64%) | 400.00K Increased by +40.00% | Dec 31, 25 |
| 9 | Janus Henderson Mid Cap Growth MA | 976.88K (1.60%) | 976.88K Increased by +100.00% | Sep 30, 25 |
| 10 | T. Rowe Price US Mid-Cap Growth Equity | 784.10K (1.29%) | -231.30K Decreased by -29.50% | Dec 31, 25 |
| 11 | T. Rowe Price Mid-Cap Growth | 783.40K (1.29%) | -700.00 Decreased by -0.09% | Jan 31, 26 |
| 12 | Janus Inst Mid Cap Growth CF | 731.87K (1.20%) | -245.01K Decreased by -33.48% | Dec 31, 25 |
| 13 | Fidelity Select Health Care | 716.00K (1.18%) | -24.00K Decreased by -3.35% | Jan 31, 26 |
| 14 | Artisan Mid Cap Investor | 705.17K (1.16%) | -112.88K Decreased by -16.01% | Dec 31, 25 |
| 15 | Artisan U.S. Mid-Cap Growth | 705.17K (1.16%) | -112.88K Decreased by -16.01% | Dec 31, 25 |
| 16 | T. Rowe Price Health Sciences | 683.90K (1.12%) | -23.22K Decreased by -3.39% | Jan 31, 26 |
| 17 | American Century US Premier Lg Cp Gr | 664.00K (1.09%) | 664.00K Increased by +100.00% | Dec 31, 25 |
| 18 | American Century Ultra® Inv | 664.00K (1.09%) | 664.00K Increased by +100.00% | Dec 31, 25 |
| 19 | Fidelity® Select Biotechnology | 659.41K (1.08%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | CTIVP Westfield Slct LgCap Gro 1 | 631.98K (1.04%) | 0.00 Increased by 0.00% | Mar 31, 25 |