| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 7.23M (13.06%) | -1.33M Decreased by -18.42% | Dec 31, 25 |
| 2 | BlackRock Inc | 6.80M (12.29%) | -86.51K Decreased by -1.27% | Sep 30, 25 |
| 3 | EcoR1 Capital, LLC | 6.73M (12.15%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Logos Global Management LP | 5.58M (10.07%) | 2.27M Increased by +40.81% | Sep 30, 25 |
| 5 | D. E. Shaw & Co LP | 3.69M (6.66%) | 342.04K Increased by +9.27% | Dec 31, 25 |
| 6 | Citadel Advisors Llc | 3.67M (6.64%) | -201.53K Decreased by -5.48% | Jun 30, 25 |
| 7 | Pfizer Inc | 3.46M (6.25%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 8 | RTW INVESTMENTS, LLC | 3.33M (6.02%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | TCG Crossover Management, LLC | 2.67M (4.82%) | 1.05M Increased by +39.34% | Dec 31, 25 |
| 10 | Bellevue Group AG | 2.39M (4.32%) | 3.00K Increased by +0.13% | Dec 31, 24 |
| 11 | Paradigm Biocapital Advisors LP | 2.34M (4.23%) | -98.19K Decreased by -4.20% | Sep 30, 24 |
| 12 | Point72 Asset Management, L.P. | 2.32M (4.18%) | 2.32M Increased by +100.00% | Dec 31, 25 |
| 13 | T. Rowe Price Investment Management,Inc. | 2.21M (3.99%) | 2.21M Increased by +100.00% | Dec 31, 24 |
| 14 | State Street Corp | 1.87M (3.38%) | 140.76K Increased by +7.52% | Sep 30, 25 |
| 15 | JPMorgan Chase & Co | 1.86M (3.35%) | -2.80M Decreased by -150.86% | Dec 31, 24 |
| 16 | Alyeska Investment Group, L.P. | 1.80M (3.25%) | 1.80M Increased by +100.00% | Mar 31, 25 |
| 17 | Armistice Capital, LLC | 1.80M (3.25%) | 600.00K Increased by +33.33% | Dec 31, 25 |
| 18 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 1.78M (3.21%) | 532.11K Increased by +29.95% | Dec 31, 24 |
| 19 | Opaleye Management Inc | 1.68M (3.03%) | -295.00K Decreased by -17.56% | Jun 30, 25 |
| 20 | Morgan Stanley - Brokerage Accounts | 1.66M (3.00%) | 78.49K Increased by +4.72% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 2.38M (4.30%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard US Total Market Shares ETF | 1.93M (3.49%) | 2.43K Increased by +0.13% | Sep 30, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.92M (3.47%) | 29.05K Increased by +1.51% | Feb 28, 26 |
| 4 | Vanguard Strategic Equity Inv | 1.62M (2.93%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 5 | iShares Russell 2000 ETF | 1.60M (2.90%) | 562.10K Increased by +35.04% | Feb 28, 26 |
| 6 | Vanguard Explorer Inv | 1.02M (1.85%) | -533.87K Decreased by -52.27% | Dec 31, 25 |
| 7 | Vanguard Small Cap Index | 841.18K (1.52%) | -5.64K Decreased by -0.67% | Jul 31, 25 |
| 8 | JPMorgan Small Cap Growth A | 755.08K (1.36%) | -8.49K Decreased by -1.12% | Feb 28, 25 |
| 9 | T. Rowe Price New Horizons | 715.98K (1.29%) | -299.48K Decreased by -41.83% | Jun 30, 25 |
| 10 | US Small-Cap Growth II Equity Comp | 715.98K (1.29%) | -1.17M Decreased by -163.57% | Jun 30, 25 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 705.08K (1.27%) | 1.91K Increased by +0.27% | Feb 28, 26 |
| 12 | T. Rowe Price Small-Cap Stock | 702.69K (1.27%) | 94.70K Increased by +13.48% | Feb 28, 25 |
| 13 | Fidelity Small Cap Index | 644.61K (1.16%) | -22.98K Decreased by -3.57% | Dec 31, 25 |
| 14 | FIAM Small Cap Core Composite | 601.40K (1.09%) | -165.20K Decreased by -27.47% | Dec 31, 24 |
| 15 | FIAM Small Cap Core CIT Cl B | 587.40K (1.06%) | -14.00K Decreased by -2.38% | Feb 28, 25 |
| 16 | iShares Russell 2000 Growth ETF | 555.88K (1.00%) | 0.00 Increased by 0.00% | May 31, 25 |
| 17 | T. Rowe Price New Horizons Tr-A | 525.56K (0.95%) | 757.00 Increased by +0.14% | Mar 31, 25 |
| 18 | T. Rowe Price New Horizons Tr-Z | 525.56K (0.95%) | 757.00 Increased by +0.14% | Mar 31, 25 |
| 19 | iShares Russell 2000 Value ETF | 507.50K (0.92%) | 507.50K Increased by +100.00% | Feb 28, 26 |
| 20 | Vanguard Strategic Small-Cap Equity Inv | 488.69K (0.88%) | -224.63K Decreased by -45.97% | Dec 31, 25 |