| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | venBio Select Advisor LLC | 12.22M (13.67%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | EcoR1 Capital, LLC | 11.90M (13.31%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Vanguard Group Inc | 10.15M (11.36%) | 24.39K Increased by +0.24% | Jun 30, 25 |
| 4 | Morgan Stanley - Brokerage Accounts | 9.75M (10.91%) | 126.08K Increased by +1.29% | Jun 30, 25 |
| 5 | Wellington Management Company LLP | 8.98M (10.04%) | -3.33M Decreased by -37.05% | Jun 30, 25 |
| 6 | JPMorgan Chase & Co | 7.77M (8.69%) | 1.41M Increased by +18.21% | Sep 30, 24 |
| 7 | Deep Track Capital, LP | 7.00M (7.83%) | 2.00M Increased by +28.57% | Jun 30, 25 |
| 8 | BlackRock Inc | 6.40M (7.16%) | 75.40K Increased by +1.18% | Jun 30, 25 |
| 9 | AQR Capital Management LLC | 5.98M (6.69%) | 1.90M Increased by +31.77% | Jun 30, 25 |
| 10 | UBS Group AG | 4.74M (5.30%) | 1.46M Increased by +30.90% | Jun 30, 25 |
| 11 | State Street Corp | 3.56M (3.99%) | -378.68K Decreased by -10.63% | Jun 30, 25 |
| 12 | T. Rowe Price Investment Management,Inc. | 2.99M (3.34%) | -1.06M Decreased by -35.61% | Sep 30, 24 |
| 13 | State Street Corporation | 2.91M (3.25%) | -5.89K Decreased by -0.20% | Mar 31, 24 |
| 14 | Suvretta Capital Management, LLC | 2.88M (3.22%) | 1.23M Increased by +42.79% | Jun 30, 25 |
| 15 | Marshall Wace Asset Management Ltd | 2.70M (3.03%) | 2.68M Increased by +99.13% | Jun 30, 25 |
| 16 | Jennison Associates LLC | 2.66M (2.98%) | 184.29K Increased by +6.92% | Jun 30, 25 |
| 17 | Siren, L.L.C. | 2.58M (2.88%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | Bank of America Corp | 2.43M (2.71%) | -704.81K Decreased by -29.04% | Jun 30, 25 |
| 19 | NORGES BANK | 2.37M (2.65%) | 1.28M Increased by +54.11% | Jun 30, 25 |
| 20 | Assenagon Asset Management SA | 2.14M (2.40%) | 1.41M Increased by +65.74% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 6.24M (6.98%) | -3.04M Decreased by -48.76% | Jun 30, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.36M (3.76%) | -70.87K Decreased by -2.11% | Jul 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 3.30M (3.69%) | 2.68K Increased by +0.08% | Sep 30, 24 |
| 4 | Vanguard Small Cap Index | 2.59M (2.90%) | -16.82K Decreased by -0.65% | Jul 31, 25 |
| 5 | US Small-Cap Growth II Equity Comp | 1.79M (2.00%) | 1.79M Increased by +100.00% | Jun 30, 23 |
| 6 | SPDR® S&P Biotech ETF | 1.76M (1.96%) | 3.92K Increased by +0.22% | Aug 31, 25 |
| 7 | Vanguard Small Cap Growth Index Inv | 1.47M (1.64%) | -725.00 Decreased by -0.05% | Jul 31, 25 |
| 8 | Polar Capital Biotech S Inc | 1.35M (1.51%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 9 | DWS Vermögensbildungsfonds I LD | 1.32M (1.48%) | 4.00 Increased by +0.00% | Jul 31, 25 |
| 10 | JPMorgan Mid Cap Growth I | 1.30M (1.46%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 11 | JPM US Mid Cap Growth-Composite | 1.30M (1.46%) | 294.66K Increased by +22.62% | Sep 30, 24 |
| 12 | T. Rowe Price Health Sciences | 1.29M (1.44%) | -29.49K Decreased by -2.28% | Mar 31, 24 |
| 13 | Fidelity® Select Biotechnology | 1.28M (1.43%) | 56.40K Increased by +4.41% | Nov 30, 23 |
| 14 | T. Rowe Price US Mid-Cap Growth Equity | 1.20M (1.34%) | -145.16K Decreased by -12.13% | Sep 30, 24 |
| 15 | Worldwide Healthcare Ord | 1.19M (1.33%) | 0.00 Increased by 0.00% | May 31, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 1.16M (1.30%) | -508.69K Decreased by -43.90% | Jul 31, 25 |
| 17 | Jennison Health Sciences Equity | 1.12M (1.26%) | 268.83K Increased by +23.91% | Jun 30, 25 |
| 18 | PGIM Jennison Health Sciences Z | 1.12M (1.26%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | T. Rowe Price US Small-Cap Core Equity | 1.09M (1.21%) | -1.60K Decreased by -0.15% | Dec 31, 23 |
| 20 | T. Rowe Price Small-Cap Stock | 1.09M (1.21%) | -1.60K Decreased by -0.15% | Dec 31, 23 |