| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Pfizer Inc | 22.03M (14.26%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | TPG GP A, LLC | 18.72M (12.12%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | BlackRock Inc | 17.90M (11.59%) | -35.51K Decreased by -0.20% | Jun 30, 25 |
| 4 | Capital World Investors | 11.15M (7.22%) | -1.12M Decreased by -10.00% | Jun 30, 25 |
| 5 | Darwin Global Management, Ltd. | 10.48M (6.78%) | 30.00K Increased by +0.29% | Jun 30, 25 |
| 6 | Citadel Advisors Llc | 10.25M (6.64%) | 49.28K Increased by +0.48% | Jun 30, 25 |
| 7 | State Street Corporation | 9.18M (5.95%) | 6.76M Increased by +73.57% | Mar 31, 24 |
| 8 | Vanguard Group Inc | 8.26M (5.35%) | 191.57K Increased by +2.32% | Jun 30, 25 |
| 9 | FMR Inc | 7.39M (4.79%) | -16.38M Decreased by -221.50% | Mar 31, 25 |
| 10 | PRIMECAP Management Company | 5.72M (3.70%) | 787.30K Increased by +13.77% | Jun 30, 25 |
| 11 | Goldman Sachs Group Inc | 5.50M (3.56%) | -350.83K Decreased by -6.38% | Jun 30, 25 |
| 12 | JPMorgan Chase & Co | 5.14M (3.33%) | 1.40M Increased by +27.27% | Mar 31, 25 |
| 13 | EcoR1 Capital, LLC | 4.49M (2.91%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | Woodline Partners LP | 4.36M (2.82%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | T. Rowe Price Associates, Inc. | 4.03M (2.61%) | -175.13K Decreased by -4.34% | Jun 30, 25 |
| 16 | Boxer Capital LLC | 3.85M (2.49%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 17 | Geode Capital Management, LLC | 3.79M (2.46%) | 435.39K Increased by +11.47% | Jun 30, 25 |
| 18 | Wildcat Capital Management, LLC | 2.92M (1.89%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 19 | Foresite Capital Management VI LLC | 2.88M (1.86%) | -572.92K Decreased by -19.93% | Jun 30, 25 |
| 20 | Dimensional Fund Advisors, Inc. | 2.74M (1.77%) | -443.43K Decreased by -16.20% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 11.15M (7.22%) | -1.12M Decreased by -10.00% | Jun 30, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 4.58M (2.97%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 3 | Vanguard US Total Market Shares ETF | 4.34M (2.81%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 4.19M (2.71%) | -92.41K Decreased by -2.21% | Jul 31, 25 |
| 5 | Fidelity Select Health Care | 4.00M (2.59%) | -350.00K Decreased by -8.75% | Jan 31, 25 |
| 6 | SPDR® S&P Biotech ETF | 3.90M (2.53%) | -23.78K Decreased by -0.61% | Feb 28, 25 |
| 7 | iShares Russell 2000 ETF | 3.58M (2.32%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 8 | Vanguard Capital Opportunity Inv | 3.56M (2.31%) | 600.00K Increased by +16.83% | Jun 30, 25 |
| 9 | Fidelity Series Small Cap Opps | 3.54M (2.29%) | -141.30K Decreased by -3.99% | Sep 30, 24 |
| 10 | Fidelity Advisor® Health Care I | 2.88M (1.87%) | 4.50K Increased by +0.16% | Nov 30, 23 |
| 11 | T. Rowe Price Health Sciences | 2.72M (1.76%) | -30.52K Decreased by -1.12% | Jul 31, 25 |
| 12 | Fidelity Advisor Health Care I | 2.50M (1.62%) | -500.00K Decreased by -20.00% | Jan 31, 25 |
| 13 | BGF World Healthscience A2 | 2.47M (1.60%) | 0.00 Increased by 0.00% | May 31, 25 |
| 14 | BGF World Healthscience A2 USD | 2.47M (1.60%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 15 | Fidelity Growth Compy Commingled Pl S | 2.46M (1.59%) | -1.31M Decreased by -53.05% | Mar 31, 25 |
| 16 | Fidelity® Select Biotechnology | 2.28M (1.47%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 17 | Fidelity Stock Selector Small Cap | 2.13M (1.38%) | 143.60K Increased by +6.73% | Sep 30, 24 |
| 18 | Fidelity Advisor Biotechnology I | 2.07M (1.34%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 19 | Fidelity® Growth Company | 2.07M (1.34%) | 20.58K Increased by +0.99% | Nov 30, 23 |
| 20 | PRIMECAP Odyssey Aggressive Growth | 2.03M (1.31%) | 187.30K Increased by +9.25% | Jun 30, 25 |