| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Pfizer Inc | 22.03M (11.76%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 2 | TPG GP A, LLC | 18.72M (9.99%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 3 | BlackRock Inc | 17.51M (9.35%) | -382.73K Decreased by -2.19% | Sep 30, 25 |
| 4 | Citadel Advisors Llc | 12.11M (6.46%) | -1.86M Decreased by -15.36% | Dec 31, 25 |
| 5 | Capital World Investors | 11.15M (5.95%) | -1.12M Decreased by -10.00% | Jun 30, 25 |
| 6 | Darwin Global Management, Ltd. | 10.48M (5.59%) | 30.00K Increased by +0.29% | Jun 30, 25 |
| 7 | Vanguard Group Inc | 9.25M (4.94%) | 230.84K Increased by +2.50% | Dec 31, 25 |
| 8 | State Street Corporation | 9.18M (4.90%) | 6.76M Increased by +73.57% | Mar 31, 24 |
| 9 | PRIMECAP Management Company | 8.14M (4.34%) | 1.06M Increased by +13.03% | Dec 31, 25 |
| 10 | FMR Inc | 7.39M (3.95%) | -16.38M Decreased by -221.50% | Mar 31, 25 |
| 11 | Goldman Sachs Group Inc | 5.50M (2.94%) | -350.83K Decreased by -6.38% | Jun 30, 25 |
| 12 | JPMorgan Chase & Co | 5.14M (2.74%) | 1.40M Increased by +27.27% | Mar 31, 25 |
| 13 | Patient Square Capital LP | 4.96M (2.65%) | 1.98M Increased by +39.94% | Dec 31, 25 |
| 14 | EcoR1 Capital, LLC | 4.49M (2.39%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | Geode Capital Management, LLC | 3.93M (2.10%) | 99.03K Increased by +2.52% | Dec 31, 25 |
| 16 | Frazier Life Sciences Management, L.P. | 3.87M (2.06%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 17 | Boxer Capital LLC | 3.85M (2.05%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 18 | T. Rowe Price Associates, Inc. | 3.68M (1.96%) | -353.40K Decreased by -9.61% | Sep 30, 25 |
| 19 | UBS Group AG | 3.57M (1.91%) | 1.53M Increased by +42.91% | Sep 30, 25 |
| 20 | Woodline Partners LP | 3.50M (1.87%) | -860.11K Decreased by -24.57% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 11.15M (5.95%) | -1.12M Decreased by -10.00% | Jun 30, 25 |
| 2 | Vanguard Capital Opportunity Inv | 5.19M (2.77%) | 768.93K Increased by +14.82% | Dec 31, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 4.88M (2.60%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 4 | Fidelity Growth Compy Commingled Pl O | 4.58M (2.44%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 5 | Vanguard US Total Market Shares ETF | 4.34M (2.31%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Fidelity Select Health Care | 4.00M (2.13%) | -350.00K Decreased by -8.75% | Jan 31, 25 |
| 7 | SPDR® S&P Biotech ETF | 3.90M (2.08%) | -23.78K Decreased by -0.61% | Feb 28, 25 |
| 8 | iShares Russell 2000 ETF | 3.78M (2.02%) | 2.05M Increased by +54.30% | Feb 28, 26 |
| 9 | Fidelity Series Small Cap Opps | 3.54M (1.89%) | -141.30K Decreased by -3.99% | Sep 30, 24 |
| 10 | Fidelity Advisor® Health Care I | 2.88M (1.54%) | 4.50K Increased by +0.16% | Nov 30, 23 |
| 11 | PRIMECAP Odyssey Aggressive Growth | 2.73M (1.45%) | 264.05K Increased by +9.69% | Dec 31, 25 |
| 12 | Fidelity Advisor Health Care I | 2.50M (1.33%) | -500.00K Decreased by -20.00% | Jan 31, 25 |
| 13 | BGF World Healthscience A2 USD | 2.47M (1.32%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 14 | Fidelity Growth Compy Commingled Pl S | 2.46M (1.31%) | -1.31M Decreased by -53.05% | Mar 31, 25 |
| 15 | BGF World Healthscience A2 | 2.44M (1.30%) | -32.17K Decreased by -1.32% | Nov 30, 25 |
| 16 | Fidelity® Select Biotechnology | 2.28M (1.22%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 17 | Fidelity Stock Selector Small Cap | 2.13M (1.14%) | 143.60K Increased by +6.73% | Sep 30, 24 |
| 18 | Fidelity Advisor Biotechnology I | 2.07M (1.11%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 19 | Fidelity® Growth Company | 2.07M (1.11%) | 20.58K Increased by +0.99% | Nov 30, 23 |
| 20 | T. Rowe Price Health Sciences | 1.98M (1.05%) | -170.89K Decreased by -8.64% | Jan 31, 26 |