| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 5.97M (15.14%) | -331.53K Decreased by -5.55% | Jun 30, 25 |
| 2 | Paradigm Biocapital Advisors LP | 4.65M (11.78%) | 156.98K Increased by +3.38% | Jun 30, 25 |
| 3 | Vanguard Group Inc | 3.94M (10.00%) | -40.27K Decreased by -1.02% | Jun 30, 25 |
| 4 | NEA Management Company, LLC | 3.75M (9.49%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | BlackRock Inc | 3.47M (8.79%) | -499.38K Decreased by -14.40% | Jun 30, 25 |
| 6 | RA Capital Management, LLC | 3.04M (7.70%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | Vestal Point Capital LP | 2.75M (6.97%) | 362.28K Increased by +13.17% | Jun 30, 25 |
| 8 | Perceptive Advisors LLC | 2.48M (6.28%) | -448.48K Decreased by -18.10% | Jun 30, 25 |
| 9 | SR ONE CAPITAL MANAGEMENT, LP | 2.35M (5.95%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | T. Rowe Price Investment Management,Inc. | 1.94M (4.93%) | 278.59K Increased by +14.33% | Jun 30, 25 |
| 11 | State Street Corporation | 1.77M (4.50%) | -240.41K Decreased by -13.55% | Dec 31, 23 |
| 12 | State Street Corp | 1.59M (4.04%) | -74.14K Decreased by -4.66% | Jun 30, 25 |
| 13 | T. Rowe Price Associates, Inc. | 1.44M (3.65%) | -400.85K Decreased by -27.86% | Jun 30, 25 |
| 14 | Novo A/S | 1.07M (2.72%) | 75.00K Increased by +6.98% | Sep 30, 23 |
| 15 | AJU IB Investment Co Ltd | 1.05M (2.65%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | HHG PLC | 1.02M (2.59%) | -486.91K Decreased by -47.57% | Jun 30, 25 |
| 17 | JPMorgan Chase & Co | 976.97K (2.48%) | 293.39K Increased by +30.03% | Jun 30, 25 |
| 18 | Geode Capital Management, LLC | 961.78K (2.44%) | -58.76K Decreased by -6.11% | Jun 30, 25 |
| 19 | Cormorant Asset Management, LLC | 800.00K (2.03%) | -250.00K Decreased by -31.25% | Jun 30, 25 |
| 20 | Capital World Investors | 783.01K (1.98%) | 73.64K Increased by +9.40% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.74M (4.40%) | -36.26K Decreased by -2.09% | Jul 31, 25 |
| 2 | Fidelity® Select Biotechnology | 1.19M (3.02%) | -167.40K Decreased by -14.04% | Nov 30, 23 |
| 3 | Fidelity Growth Compy Commingled Pl S | 1.03M (2.60%) | 101.33K Increased by +9.88% | Jul 31, 25 |
| 4 | iShares Russell 2000 ETF | 882.89K (2.24%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 5 | American Funds SMALLCAP World A | 783.01K (1.98%) | 73.64K Increased by +9.40% | Jun 30, 25 |
| 6 | Fidelity Growth Company Fund | 773.52K (1.96%) | 81.07K Increased by +10.48% | Jul 31, 25 |
| 7 | SPDR® S&P Biotech ETF | 688.11K (1.74%) | 1.53K Increased by +0.22% | Aug 31, 25 |
| 8 | Vanguard Small Cap Index | 668.59K (1.69%) | -4.27K Decreased by -0.64% | Jul 31, 25 |
| 9 | T. Rowe Price Small-Cap Stock | 587.70K (1.49%) | 87.33K Increased by +14.86% | Jul 31, 25 |
| 10 | Fidelity Select Biotechnology | 552.00K (1.40%) | -19.90K Decreased by -3.61% | Jul 31, 25 |
| 11 | T. Rowe Price US Small-Cap Core Equity | 500.37K (1.27%) | -28.93K Decreased by -5.78% | Jun 30, 25 |
| 12 | Janus Henderson Global Life Sciences D | 484.24K (1.23%) | -6.26K Decreased by -1.29% | Sep 30, 24 |
| 13 | Fidelity Small Cap Growth | 483.71K (1.23%) | -4.11K Decreased by -0.85% | Jun 30, 25 |
| 14 | JPMorgan Small Cap Growth A | 465.31K (1.18%) | -5.01K Decreased by -1.08% | Jul 31, 25 |
| 15 | UBS: US Equity Small Cap Growth | 444.31K (1.13%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | US Small-Cap Growth II Equity Comp | 439.73K (1.11%) | -21.65K Decreased by -4.92% | Jun 30, 25 |
| 17 | Lord Abbett Developing Growth A | 435.68K (1.10%) | -73.45K Decreased by -16.86% | Jan 31, 25 |
| 18 | Fidelity Select Health Care | 430.00K (1.09%) | -30.00K Decreased by -6.98% | Jul 31, 25 |
| 19 | Vanguard Institutional Extnd Mkt Idx Tr | 425.80K (1.08%) | -188.32K Decreased by -44.23% | Jul 31, 25 |
| 20 | Fidelity Growth Compy Commingled Pl O | 422.71K (1.07%) | 354.51K Increased by +83.87% | Mar 31, 24 |