| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 27.53M (13.31%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | ING Investment Management LLC | 21.25M (10.28%) | 10.62M Increased by +50.00% | Mar 31, 25 |
| 3 | Capital World Investors | 13.36M (6.46%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 4 | Baillie Gifford & Co Limited. | 10.36M (5.01%) | -835.83K Decreased by -8.07% | Jun 30, 25 |
| 5 | UBS Asset Mgmt Americas Inc | 8.47M (4.10%) | -7.20M Decreased by -84.98% | Jun 30, 25 |
| 6 | Two Sigma Investments LLC | 5.81M (2.81%) | 635.84K Increased by +10.94% | Dec 31, 25 |
| 7 | Two Sigma Advisers, LLC | 4.88M (2.36%) | 78.10K Increased by +1.60% | Dec 31, 25 |
| 8 | Credit Suisse First Boston (CSFB) | 4.55M (2.20%) | -30.93K Decreased by -0.68% | Mar 31, 24 |
| 9 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 4.11M (1.99%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 10 | Founders Fund VII Management, LLC | 3.77M (1.82%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 11 | Driehaus Capital Management LLC | 3.77M (1.82%) | 2.05M Increased by +54.22% | Dec 31, 25 |
| 12 | BlackRock Inc | 3.64M (1.76%) | -39.02K Decreased by -1.07% | Sep 30, 25 |
| 13 | Orbimed Advisors, LLC | 3.34M (1.62%) | -836.20K Decreased by -25.00% | Jun 30, 25 |
| 14 | Prosight Management, LP | 2.82M (1.36%) | -4.53M Decreased by -161.04% | Mar 31, 25 |
| 15 | Morgan Stanley - Brokerage Accounts | 2.79M (1.35%) | 1.80M Increased by +64.30% | Sep 30, 25 |
| 16 | TANG CAPITAL MANAGEMENT LLC | 2.60M (1.26%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 17 | UBS Group AG | 2.49M (1.20%) | -958.73K Decreased by -38.52% | Sep 30, 25 |
| 18 | Bank of America Corp | 2.42M (1.17%) | 2.19M Increased by +90.72% | Sep 30, 25 |
| 19 | Renaissance Technologies Corp | 2.39M (1.16%) | -971.50K Decreased by -40.66% | Dec 31, 25 |
| 20 | Casdin Capital, LLC | 2.36M (1.14%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 13.36M (6.46%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | Allianz Global Artfcl Intlgc W EUR | 6.17M (2.99%) | -7.81K Decreased by -0.13% | Apr 30, 25 |
| 3 | CS (Lux) Digital Health Equity SB USD | 4.50M (2.18%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 4 | UBS (Lux) Digital Health Equity SB USD | 4.50M (2.18%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 5 | SMDS Global AI Equity Mother | 4.49M (2.17%) | 0.00 Increased by 0.00% | Mar 25, 25 |
| 6 | Baillie Gifford Positive Change | 3.89M (1.88%) | -143.60K Decreased by -3.69% | Jul 31, 25 |
| 7 | Baillie Gifford Positive Change B Acc | 3.89M (1.88%) | -128.37K Decreased by -3.30% | Jul 31, 25 |
| 8 | UBS Lux Dgtl Hlth Eq Fd seeding P acc | 2.93M (1.42%) | -181.25K Decreased by -6.18% | Nov 30, 25 |
| 9 | American Funds IS® Asset Allocation 1 | 2.87M (1.39%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 10 | Baillie Gifford WW Pstv Chg B USD Acc | 2.26M (1.09%) | -72.26K Decreased by -3.20% | Jul 31, 25 |
| 11 | ACATIS Datini Valueflex Fonds A | 1.86M (0.90%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 12 | iShares Biotechnology ETF | 1.73M (0.84%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 13 | Desjardins Global Small Cap Equity A | 1.29M (0.63%) | 22.03K Increased by +1.70% | Jan 31, 24 |
| 14 | Lazard Global Small Cap Equity | 1.29M (0.63%) | 114.74K Increased by +8.88% | Dec 31, 23 |
| 15 | Nissay Glb Digital Hlthcare Equity MF | 974.00K (0.47%) | 149.70K Increased by +15.37% | Nov 20, 23 |
| 16 | Nissay Glbl Digital Hlthcare Eq MF | 962.50K (0.47%) | 139.50K Increased by +14.49% | Nov 18, 24 |
| 17 | Baillie Gifford International Alpha 2 | 835.46K (0.40%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 18 | Heptagon Driehaus US Micro Cap Eq C$ Acc | 637.73K (0.31%) | 637.73K Increased by +100.00% | Jan 31, 26 |
| 19 | BlackRock Global Equity Mkt Netrl Instl | 564.25K (0.27%) | 33.07K Increased by +5.86% | Apr 30, 24 |
| 20 | State Street® SPDR® Ptf Dev Wld exUS ETF | 548.70K (0.27%) | -3.55K Decreased by -0.65% | Feb 27, 26 |